Pesquisa | Secretaria de Estado da Saúde

1.

CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.

Huang, Shouxiong; Shahine, Adam; Cheng, Tan-Yun; Chen, Yi-Ling; Ng, Soo Weei; Balaji, Gautham R; Farquhar, Rachel; Gras, Stephanie; Hardman, Clare S; Altman, John D; Tahiri, Nabil; Minnaard, Adriaan J; Ogg, Graham S; Mayfield, Jacob A; Rossjohn, Jamie; Moody, D Branch.

Cell ; 186(21): 4583-4596.e13, 2023 10 12.

Artigo Inglês | MEDLINE | ID: mdl-37725977

2.

Complex effects of sequence variants on lipid levels and coronary artery disease.

Snaebjarnarson, Audunn S; Helgadottir, Anna; Arnadottir, Gudny A; Ivarsdottir, Erna V; Thorleifsson, Gudmar; Ferkingstad, Egil; Einarsson, Gudmundur; Sveinbjornsson, Gardar; Thorgeirsson, Thorgeir E; Ulfarsson, Magnus O; Halldorsson, Bjarni V; Olafsson, Isleifur; Erikstrup, Christian; Pedersen, Ole B; Nyegaard, Mette; Bruun, Mie T; Ullum, Henrik; Brunak, Søren; Iversen, Kasper Karmark; Christensen, Alex Hoerby; Olesen, Morten S; Ghouse, Jonas; Banasik, Karina; Knowlton, Kirk U; Arnar, David O; Thorgeirsson, Gudmundur; Nadauld, Lincoln; Ostrowski, Sisse Rye; Bundgaard, Henning; Holm, Hilma; Sulem, Patrick; Stefansson, Kari; Gudbjartsson, Daniel F.

Cell ; 186(19): 4085-4099.e15, 2023 09 14.

Artigo Inglês | MEDLINE | ID: mdl-37714134

3.

Structure and Mechanism of the Lipid Flippase MurJ.

Kuk, Alvin C Y; Hao, Aili; Lee, Seok-Yong.

Annu Rev Biochem ; 91: 705-729, 2022 06 21.

Artigo Inglês | MEDLINE | ID: mdl-35320686

4.

T cell antigen receptor recognition of antigen-presenting molecules.

Rossjohn, Jamie; Gras, Stephanie; Miles, John J; Turner, Stephen J; Godfrey, Dale I; McCluskey, James.

Annu Rev Immunol ; 33: 169-200, 2015.

Artigo Inglês | MEDLINE | ID: mdl-25493333

5.

Accurate de novo design of membrane-traversing macrocycles.

Bhardwaj, Gaurav; O'Connor, Jacob; Rettie, Stephen; Huang, Yen-Hua; Ramelot, Theresa A; Mulligan, Vikram Khipple; Alpkilic, Gizem Gokce; Palmer, Jonathan; Bera, Asim K; Bick, Matthew J; Di Piazza, Maddalena; Li, Xinting; Hosseinzadeh, Parisa; Craven, Timothy W; Tejero, Roberto; Lauko, Anna; Choi, Ryan; Glynn, Calina; Dong, Linlin; Griffin, Robert; van Voorhis, Wesley C; Rodriguez, Jose; Stewart, Lance; Montelione, Gaetano T; Craik, David; Baker, David.

Cell ; 185(19): 3520-3532.e26, 2022 09 15.

Artigo Inglês | MEDLINE | ID: mdl-36041435

6.

Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome.

Kawano, Yoshinaga; Edwards, Madeline; Huang, Yiming; Bilate, Angelina M; Araujo, Leandro P; Tanoue, Takeshi; Atarashi, Koji; Ladinsky, Mark S; Reiner, Steven L; Wang, Harris H; Mucida, Daniel; Honda, Kenya; Ivanov, Ivaylo I.

Cell ; 185(19): 3501-3519.e20, 2022 09 15.

Artigo Inglês | MEDLINE | ID: mdl-36041436

7.

Cerebrospinal fluid immune dysregulation during healthy brain aging and cognitive impairment.

Piehl, Natalie; van Olst, Lynn; Ramakrishnan, Abhirami; Teregulova, Victoria; Simonton, Brooke; Zhang, Ziyang; Tapp, Emma; Channappa, Divya; Oh, Hamilton; Losada, Patricia M; Rutledge, Jarod; Trelle, Alexandra N; Mormino, Elizabeth C; Elahi, Fanny; Galasko, Douglas R; Henderson, Victor W; Wagner, Anthony D; Wyss-Coray, Tony; Gate, David.

Cell ; 185(26): 5028-5039.e13, 2022 12 22.

Artigo Inglês | MEDLINE | ID: mdl-36516855

8.

Learning lessons from lipids to make COVID-19 vaccines.

Cell ; 185(8): 1279-1282, 2022 04 14.

Artigo Inglês | MEDLINE | ID: mdl-35385689

9.

Fundamental behaviors emerge from simulations of a living minimal cell.

Thornburg, Zane R; Bianchi, David M; Brier, Troy A; Gilbert, Benjamin R; Earnest, Tyler M; Melo, Marcelo C R; Safronova, Nataliya; Sáenz, James P; Cook, András T; Wise, Kim S; Hutchison, Clyde A; Smith, Hamilton O; Glass, John I; Luthey-Schulten, Zaida.

Cell ; 185(2): 345-360.e28, 2022 01 20.

Artigo Inglês | MEDLINE | ID: mdl-35063075

10.

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.

Guilliams, Martin; Bonnardel, Johnny; Haest, Birthe; Vanderborght, Bart; Wagner, Camille; Remmerie, Anneleen; Bujko, Anna; Martens, Liesbet; Thoné, Tinne; Browaeys, Robin; De Ponti, Federico F; Vanneste, Bavo; Zwicker, Christian; Svedberg, Freya R; Vanhalewyn, Tineke; Gonçalves, Amanda; Lippens, Saskia; Devriendt, Bert; Cox, Eric; Ferrero, Giuliano; Wittamer, Valerie; Willaert, Andy; Kaptein, Suzanne J F; Neyts, Johan; Dallmeier, Kai; Geldhof, Peter; Casaert, Stijn; Deplancke, Bart; Ten Dijke, Peter; Hoorens, Anne; Vanlander, Aude; Berrevoet, Frederik; Van Nieuwenhove, Yves; Saeys, Yvan; Saelens, Wouter; Van Vlierberghe, Hans; Devisscher, Lindsey; Scott, Charlotte L.

Cell ; 185(2): 379-396.e38, 2022 01 20.

Artigo Inglês | MEDLINE | ID: mdl-35021063

11.

Preparing Better Samples for Cryo-Electron Microscopy: Biochemical Challenges Do Not End with Isolation and Purification.

Glaeser, Robert M.

Annu Rev Biochem ; 90: 451-474, 2021 06 20.

Artigo Inglês | MEDLINE | ID: mdl-33556280

12.

Structural snapshots of TRPV1 reveal mechanism of polymodal functionality.

Zhang, Kaihua; Julius, David; Cheng, Yifan.

Cell ; 184(20): 5138-5150.e12, 2021 09 30.

Artigo Inglês | MEDLINE | ID: mdl-34496225

13.

Structural basis for VIPP1 oligomerization and maintenance of thylakoid membrane integrity.

Gupta, Tilak Kumar; Klumpe, Sven; Gries, Karin; Heinz, Steffen; Wietrzynski, Wojciech; Ohnishi, Norikazu; Niemeyer, Justus; Spaniol, Benjamin; Schaffer, Miroslava; Rast, Anna; Ostermeier, Matthias; Strauss, Mike; Plitzko, Jürgen M; Baumeister, Wolfgang; Rudack, Till; Sakamoto, Wataru; Nickelsen, Jörg; Schuller, Jan M; Schroda, Michael; Engel, Benjamin D.

Cell ; 184(14): 3643-3659.e23, 2021 07 08.

Artigo Inglês | MEDLINE | ID: mdl-34166613

14.

Lipid Transport Across Bacterial Membranes.

Giacometti, Sabrina I; MacRae, Mark R; Dancel-Manning, Kristen; Bhabha, Gira; Ekiert, Damian C.

Annu Rev Cell Dev Biol ; 38: 125-153, 2022 10 06.

Artigo Inglês | MEDLINE | ID: mdl-35850151

15.

Macrophage function in adipose tissue homeostasis and metabolic inflammation.

Chavakis, Triantafyllos; Alexaki, Vasileia Ismini; Ferrante, Anthony W.

Nat Immunol ; 24(5): 757-766, 2023 05.

Artigo Inglês | MEDLINE | ID: mdl-37012544

16.

Regulation of membrane protein structure and function by their lipid nano-environment.

Levental, Ilya; Lyman, Ed.

Nat Rev Mol Cell Biol ; 24(2): 107-122, 2023 02.

Artigo Inglês | MEDLINE | ID: mdl-36056103

17.

SLeuthing Tuberculous Cough.

Behr, Marcel A; Edelstein, Paul H; Ramakrishnan, Lalita.

Cell ; 181(2): 230-232, 2020 04 16.

Artigo Inglês | MEDLINE | ID: mdl-32302566

18.

Genetic Screen for Cell Fitness in High or Low Oxygen Highlights Mitochondrial and Lipid Metabolism.

Jain, Isha H; Calvo, Sarah E; Markhard, Andrew L; Skinner, Owen S; To, Tsz-Leung; Ast, Tslil; Mootha, Vamsi K.

Cell ; 181(3): 716-727.e11, 2020 04 30.

Artigo Inglês | MEDLINE | ID: mdl-32259488

19.

TACAN Is an Ion Channel Involved in Sensing Mechanical Pain.

Beaulieu-Laroche, Lou; Christin, Marine; Donoghue, Annmarie; Agosti, Francina; Yousefpour, Noosha; Petitjean, Hugues; Davidova, Albena; Stanton, Craig; Khan, Uzair; Dietz, Connor; Faure, Elise; Fatima, Tarheen; MacPherson, Amanda; Mouchbahani-Constance, Stephanie; Bisson, Daniel G; Haglund, Lisbet; Ouellet, Jean A; Stone, Laura S; Samson, Jonathan; Smith, Mary-Jo; Ask, Kjetil; Ribeiro-da-Silva, Alfredo; Blunck, Rikard; Poole, Kate; Bourinet, Emmanuel; Sharif-Naeini, Reza.

Cell ; 180(5): 956-967.e17, 2020 03 05.

Artigo Inglês | MEDLINE | ID: mdl-32084332

20.

Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough.

Ruhl, Cody R; Pasko, Breanna L; Khan, Haaris S; Kindt, Lexy M; Stamm, Chelsea E; Franco, Luis H; Hsia, Connie C; Zhou, Min; Davis, Colton R; Qin, Tian; Gautron, Laurent; Burton, Michael D; Mejia, Galo L; Naik, Dhananjay K; Dussor, Gregory; Price, Theodore J; Shiloh, Michael U.

Cell ; 181(2): 293-305.e11, 2020 04 16.

Artigo Inglês | MEDLINE | ID: mdl-32142653

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